Tanpro® (50% Tannalbin) – Especially Effecitve for Piglets

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(50% Tannalbin-Stablized Tannins)

-The milestone of the Innovative livestock feed additives

The chemical composition of Tanpro® : 50% Tannalbin-Stablized Tannins

Tannalbin is a typical antidiarrheal medicine embodied into:

1) many national Pharmacopoeias including Chinese Pharmacopeia, Japanese Pharmacopoeia (JP), and German Pharmacopoeia (Deutsches Arzneibuch – DAB);

2) veterinary Pharmacology textbooks and veterinary drug handbooks

Cas No.: 10361-46-3

Synonyms: Albutannin; Albutannins; Tannalbin; Tannalbins; Tannin albuminate; Albumintannate

Typical Physical Properties Physical appearance:White Microgranules

Unique Characteristics and Functions:

Intestinal convergence: it insures the completeness of animals’ mucosa, effectively reduces the rates of diarrhea and promotes the animal production performance & the feed conversion efficiency.

  • Neutralizing the enterotoxins of Escherichia coli (LT) and the exotoxin produced by other bacteria, thence to control diarrhea.
  • Easy to use: Tanpro® employs tannin acid of a special structure, which is different from the free (isolated) tannin acid. Having no irritation to the operators’ skin, it brings great convenience in production and operation; it does not distain the feed processing machines; when added into feed, it does not blacken in touch with water; meanwhile, the tannin acid is stablized consequently.
  • Absolutely palatable: Tannalbin is insoluble in water. Tannic acid is only released on condtition that the GUT is alkaline. Therefore the palatability problem is out of the question; It enables the intestinal tract to achieve a target release and a double anti-diarrheal effect of  the free tannin acid [1 Kg Tanpro®  (50%) = 1.5 Kg free tannin acid (70%)].
  • High-performance alternative or supplement: Tanpro® can completely substitute antibiotic growth promoters (AGPs) and/or high-dose ZnO or spray-dried animal plasma (SDPP) while they are forbidden or during the “No-Antibiotics Feed” period.
  • GRAS Substances: Tanpro® can be administered to all animal subjects at any growth stages, without withdrawal periods.

Feeding Trials with Adminstration of Tanpro®

Table 1. The effect of Tanpro add into the creep feed
Table 1-Pro-Tan

The dose regimen of the control group:ZnO 2250ppm + Bacillus sulfate 20ppm + chlortetracycline 75ppm; The dose regimen of “Tanpro” group: ZnO 2250ppm + chlortetracycline 75ppm +Tanpro 1500ppm. ②Test location: Insighter animal experiment farm (Jiangmen,Guangdong); ③Time of the experiment:6th.,May~16th,May.,2015. ④Animal for experiment: Duroc dasanyuan hybrid piglet,25 days of age;  ⑤Feed: Custom creep feed, nutritious level: simple protein≥18.0%, crude fiber ≤4.0%,crude ash≤7.0%,calcium 0.5-1.2%,total phosphorus≥0.55%,Lys≥1.5%,DE 3500kcal/kg。It  including 5% SDPP on both of group

Table 2. The effect that Tanpro replace the SDPP when add into the creep feed

Table 2-Pro-TanRemark:①The dose regimen of the SDPP group:SDPP 5%;ZnO 2250ppm+Bacillus Sulfate 20ppm+chlortetracycline 75ppm;The dose regimen of the Tanpro group:Choice the equal amount of SPC to replace the SDPP ;ZnO 2250ppm+Bacillus Sulfate 20ppm +chlortetracycline 75ppm+Tanpro 10000ppm。②Place of examination:The animal examination farm of Ingishter(Jiangmen,Guangdong);③Examination Date:8th.,~18th.,June.;④Animal for experiment: :Duroc dasanyuan hybrid piglet,25 days of age;;⑤Feed:custom creep feed,nutritious level:simple protein≥18.0%,crude fiber≤4.0%,crude ash≤7.0%,calcium 0.5-1.2%,total phosphorus≥0.55%,Lys≥1.5%,DE 3500kcal/kg。

Table 3 The effect of Tanpro on the piglet nursery stage

Table 3-Pro-Tan

Remark:The dose regimen of the control group:ZnO 2250ppm+Bacillus Sulfate 20ppm+Chlortetrackcline 75ppm;“The dose regimen of Tanpro group:(ZnO)2250ppm+Bacillus Sulfate 20ppm+Chlortetrackcline 75ppm+Tanpro 1000ppm。②Place of Examination :The animal examination farm of Insighter (Jiangmen, Guangdong);③Date of examination:16th.,May~30th.,May.,2015;④The pig for examination:Duroc dasanyuan hybrid piglet,35 days of age;⑤Feed:Custom nursery feed powder, nutritious level :simple protein≥18.0%,DE 3500kcal/kg.

Table 4 The effect of Tanpro in the piglet station

Table 4-Pro-Tan

Remark:①The dose regimen of the control group:Cu 200ppm(TBCC)+Bacillus Sulfate 20ppm+Chlortetrackcline 75ppm+Quincetone 50ppm;The dose regimen of Tanpro Group:Cu 200ppm(TBCC)+Bacillus Sulfate 20ppm+Chilortetrackcline 75ppm+Quincetone 50ppm +Tanpro 500ppm;②Place of examination:The animal examination farm of Insighter(jiangmen,Guangdong);③The date of examinate:30th My~29th. June.., 2015;④Animal for examinate:Duroc dasanyuan hybrid pig,in 49 days of age。⑤Feed:Custom commercial piggy feed powder, no any ZnO and AGPs feed additives.

Table 5 The treatment effect of Tanpro for piglet early weaning diarrhea

Table 5-Pro-Tan

Remark:No feeding wean piglet for the feed powder without any AGPs,ZnO and Cu 3 days before the examination. Only choice the diarrhea wean piglet ( in 35 days of age) for examination。①The dose regimen of the control group:No any ZnO,Cu and AGPs additive;The dose regimen of Tanpro Group:Tanpro 10kg/t;②Place of examination: the examination farm of Insighte (Jiangmen, Guangdong);③Date of Examination:May.,D1(The first day for treatment);D2(The second day for treatment)……

Table 6 The effect of Tanpro for Broiler

Table 6-Pro-Tan

Remark:①The dose regimen of control group:Bacillus sulfate 20ppm+STAFAC 40g/t(1-21 days of age),Bacillus Sulfate 20ppm+STAFAC 20g/t(22-56 days of age;The dose regimen of Tanpro Group:Tanpro 300g/t(1-21 days of age) or 200 g/t(22-56 days of age);②Place of examination:Animal examination farm of Insighter( Jiangmen,Guangdong);③Date of examination:2nd.,April~27th May. 2015 ;④Animal for examination:Quick rhubarb feather broiler, the examination period is 56 days。⑤Feed: Custom commercial broiler fee, without any AGPs.

How to use

Tanrpo could replace the SDDP when add into the Creep feed (1kg replace 5 kg, the simple protein (SPC,EFFS or FSBM ) to replace the common protein in equal level. It could replace forall porcine peptom and whey powder and Fish meal on the nursery stage; it could replace fish meal on the piglet stage.

The quantity of doses recommend:

Table 7-Pro-Tan