The stability research of sodium butyrate in course of processing

“…those (the loss rates) were 32.0% (powdery sodium butyrate), 28.0% (granular sodium butyrate)  respectively when the moisture of feed was above 14~16%” Loss Rates: 28% to 32%! “When the pelleting temperature ranged from 78℃ to 81℃ to 85℃, the loss rate of powdery sodium butyrate ranged from 67.1% to 67.9% to 68.7% respectively, the loss rate of granular of sodium butyrate ranged from 36.5% t
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Is “Enteric” Necessary for Butyrate? 丁酸盐所谓的“肠溶”是个伪命题!

The following article is from the internet and for your kind reference and comments: 外界对丁酸盐原粉存在两种误解: 1)丁酸盐如果没用脂肪包被的话过不了胃部! 2)由于后肠道是碱性环境,所以丁酸易被解离, 以阴离子形式存在, 而丁酸根阴离子是没有效果的,因无法被吸收,也无杀菌能力! 他们的理由是: 1)丁酸盐在胃部被溶解,而丁酸透过胃壁被吸收掉了。 2)有机酸在不同酸碱值下被解离的情形如下: 解离/非解离 有机酸种类 pKa pH 4 pH 6 pH 7 甲酸 3.75 1.8 : 1 178 : 1 1778 : 1 乳酸 3.83 1.5 : 1 148 : 1 1479 : 1 苯甲酸 4.19 0.6 : 1 65 : 1 646 : 1 丁酸 4.86 0.1 : 1 15 : 1 138 : 1 丙酸 4.88 0.1 : 1 13
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In vitro dissolution and in vivo absorption of calcium [1-14C]butyrate in free or protected forms

http://www.feedadditive.com/docs/in-vitro-dissolution-and-in-vivo-absorption-of-calcium-1-14-cbutyrate.pdf Submitted to: Journal of Agricultural and Food Chemistry Publication Type: Peer Reviewed Journal Publication Acceptance Date: 3/8/2012 Publication Date: 3/8/2012 Citation: Smith, D.J., Barri, A., Herges, G.R., Hahn, J., Yersin, A.G., Jourdan, A. 2012. In vitro dissolution and in vivo absorption of calcium [1-14C
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Absorption, transport and metabolism of butyrate

https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0954422410000247 http://www.feedadditive.com/docs/S0954422410000247.pdf Absorption of butyrate, SCFA membrane receptor and transport proteins Earlier studies have demonstrated that SCFA are absorbed in both the small and large intestine by similar mechanisms(65,66). More recent studies suggest the existence of species differences and different t
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From the gut to the peripheral tissues: the multiple effects of butyrate

https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0954422410000247 http://www.feedadditive.com/docs/S0954422410000247.pdf Butyrate is a natural substance present in biological liquids and tissues. The present paper aims to give an update on the biological role of butyrate in mammals, when it is naturally produced by the gastrointestinal microbiota or orally ingested as a feed additive. Recent d
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Effects of plasma aldosterone on butyrate absorption and metabolism in the rabbit proximal colon

  1. Butyrate absorption in the proximal colon of the anaesthetized rabbit was evaluated by measuring the variations in the concentration of butyrate in colonie loops and in arterial and venous plasmas; metabolic conversions were studied using (3,4-14C) butyrate. 2. 2. Interrelations between butyrate absorption and metabolism and the excretory cycle of the rabbit were examined, as well as the effects of exogenou
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Butyrate and the colonocyte. Production, absorption, metabolism, and therapeutic implications.

Velázquez OC1, Lederer HM, Rombeau JL. Abstract Butyrate, a SCFA generated by microbial fermentation of dietary substrates, is produced in the colon of humans and may influence colonic disease. It is possible to manipulate the diet in order to enhance levels of butyrate in various regions of the large intestine. Butyrate is absorbed by colonocytes in the proximal colon via passive diffusion and by active transport me
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Butyrate: Short-chain fatty acids Absorption

Short-chain fatty acids and medium-chain fatty acids are primarily absorbed through the portal vein during lipid digestion,[6] while long-chain fatty acids are packed into chylomicrons and enter lymphatic capillaries, and enter the blood first at the subclavian vein. https://en.wikipedia.org/wiki/Short-chain_fatty_acid Kuksis, Arnis (2000). “Biochemistry of Glycerolipids and Formation of Chylomicrons”. In
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Butyrate: Feeding the Gut and Beyond for Animal Health

James Pierce, MS, PhD; Nutriad Inc. Elgin, IL, USA – Maja Marien, DVM, PhD; Tim Goossens, PhD; Nutriad International NV Dendermonde, Belgium Introduction In North America, there has been a tremendous body of research in recent years to find the ideal product or program to replace or reduce the use of antibiotics in livestock and poultry production. This is driven by the legislation in the EU and the pressure the heal
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